Download Files:
GSK121
$160 – $550
Products Details
Product Description
– GSK-121 Trifluoroacetates a selective PAD4 inhibitor[1].
Web ID
– HY-117777
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H26F3N5O3
References
– [1]Drewes G, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11(3):189-91.
CAS Number
– 1652591-80-4
Molecular Weight
– 501.50
Compound Purity
– 99.81
SMILES
– NC1CCCN(C1)C(C2=CC3=C(C=C2)N(C)C(C4=CC5=C(N4C)C=CC=C5)=N3)=O.OC(C(F)(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– Protein Arginine Deiminase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
