GSK-3β inhibitor 2

SKU T11471-5 mg Category Brand:

Price range: 80 CAD through 315 CAD

Products Details

Product Description

– GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50 = 1.1 nM). GSK-3β inhibitor 2 can be used in studies about Alzheimer’s disease.

Web ID

– T11471

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H14N4O3S

References

– Sivaprakasam P, et al. Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorg Med Chem Lett. 2015 May 1;25(9):1856-63.

CAS Number

– 1702428-31-6

Molecular Weight

– C14H14N4O3S

Compound Purity

– 0.9908

SMILES

– COc1nc(sc1C(N)=O)-c1ccnc(NC(=O)C2CC2)c1

Target

– GABA Receptor

Pathway

– PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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