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GSK-3484862
Price range: 69 CAD through 2,480 CAD
Products Details
Product Description
– GSK-3484862 is a non-covalent Dnmt1 inhibitor that induces DNA hypomethylation, offering potential therapeutic benefits against cancer.
Web ID
– T11469
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H19N5OS
Citations
– 1. Zhang P, Zhang Z, Wang Y, et al.A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine.EMBO reports.2025: 1-38.
References
– Azevedo Portilho N, et al. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. Epigenetics Chromatin. 2021 Dec 15;14(1):56.
CAS Number
– 2170136-65-7
Molecular Weight
– C19H19N5OS
Compound Purity
– 1
SMILES
– CCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N(C)C)c1C#N
Target
– ROR
Pathway
– Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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