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GSK-3β inhibitor 14

$313

Only 1000 item(s) left in stock.

Products Details

Product Description

– GSK-3β inhibitor 14 (Compound 6i), benzothiazepinone derivative, is a weak GSK-3β inhibitor (IC50 >100 μM)[1].

Web ID

– HY-153760

Shipping

– Room temperature

Molecular Formula

– C17H17NOS

References

– [1]Zhang P, et al. Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Eur J Med Chem. 2013 Mar;61:95-103.

CAS Number

– 863004-48-2

Molecular Weight

– 283.39

SMILES

– O=C1CC(C)SC2=CC=CC=C2N1CC3=CC=CC=C3

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– GSK-3

Pathway

– PI3K/Akt/mTOR;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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