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GSK-3β inhibitor 1
$200 – $950
Products Details
Product Description
– GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
Web ID
– HY-126144
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C14H10N2O
References
– [1]Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
CAS Number
– 187325-53-7
Molecular Weight
– 222.25
Compound Purity
– 98.04
SMILES
– O=C1NC2=CC=CC=C2/C1=C/C3=NC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– GSK-3
Isoform
– GSK-3β
Pathway
– PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
