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Products Details
Product Description
– GSK-2250665A (Compound 13) is a selective Itk inhibitor with a pKi of 9.2.
Web ID
– HY-120559
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H29N5OS
References
– [1]Alder CM, et al. Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy. ACS Med Chem Lett. 2013 Aug 12;4(10):948-52.
CAS Number
– 1246030-96-5
Molecular Weight
– 459.61
SMILES
– CCC1=CC=C2C(SC(NC3=NC(N[C@H]4CC[C@@H](CC4)O)=NC(CC5=CC=CC=C5)=C3)=N2)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Itk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
