GS-829845
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GS-829845

SKU T67905-5 mg Category Brand:

Price range: 62 CAD through 205 CAD

Products Details

Product Description

– GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life than the parent.

Web ID

– T67905

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H19N5O2S

References

– Meng A, et al. Exposure-response relationships for the efficacy and safety of filgotinib and its metabolite GS-829845 in subjects with rheumatoid arthritis based on phase 2 and phase 3 studies. Br J Clin Pharmacol. 2022;88(7):3211-3221.

CAS Number

– 1257705-09-1

Molecular Weight

– C17H19N5O2S

Compound Purity

– 0.9978

SMILES

– Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1

Pathway

– Angiogenesis|||Metabolism|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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