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Product Description
– GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 μM.
Web ID
– T36440
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H31N5O7
References
– Mackman, R.L., Hui, H.C., Perron, M., et al.Prodrugs of a 1’-CN-4-aza-7,9-dideazaadenosine C-nucleoside leading to the discovery of remdesivir (GS-5734) as a potent inhibitor of respiratory syncytial virus with efficacy in the african green monkey model of RSVJ. Med. Chem.64(8)5001-5017(2021)
CAS Number
– 2563617-99-0
Molecular Weight
– C24H31N5O7
SMILES
– CC(C)C(=O)OC[C@H]1O[C@@](C#N)([C@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)c1ccc2c(N)ncnn12
Pathway
– Others
Product type
– Small Compound
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