GPX4-IN-5
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GPX4-IN-5

SKU T77755-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 1,387 CAD

Products Details

Product Description

– GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.GPX4-IN-5 induces ferroptosis and can be used for the prevention and treatment of triple-negative breast cancer (TNBC).

Web ID

– T77755

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H17ClFNO5

References

– Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

CAS Number

– 2922824-09-5

Molecular Weight

– C18H17ClFNO5

Compound Purity

– 0.9958

SMILES

– O=C(N(C1=CC=C2OCCOC2=C1)C3=CC(OC)=C(F)C(OC)=C3)CCl

Pathway

– Oxidation-Reduction

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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