GNF4877
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GNF4877

SKU T11447-1 mg Category Brand:

Price range: 203 CAD through 2,960 CAD

Products Details

Product Description

– GNF4877 is a potent inhibitor of DYRK1A and GSK3β (IC50s: 6 nM and 16 nM, respectively), resulting in the blockade of nuclear export of nuclear factor of activated T-cells (NFATc) and increased β-cell proliferation.

Web ID

– T11447

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H27FN6O4

References

– Shen W, et al. Inhibition of DYRK1A and GSK3β induces human β-cell proliferation. Nat Commun. 2015 Oct 26;6:8372.

CAS Number

– 2041073-22-5

Molecular Weight

– C25H27FN6O4

Compound Purity

– 0.994

SMILES

– CC(C)Oc1ccc(F)c(c1)-c1cnc(N)c(n1)C(=O)Nc1cnccc1N1CCC[C@H](C1)C(O)=O

Target

– HCV Protease

Pathway

– Stem Cells|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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