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GNF351
Price range: 59 CAD through 1,592 CAD
Products Details
Product Description
– GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM).
Web ID
– T15410
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H25N7
References
– van den Bogaard EH,et al. Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation. J Invest Dermatol. 2015 May;135(5):1320-1328.
CAS Number
– 1227634-69-6
Molecular Weight
– C24H25N7
Compound Purity
– 0.9904
SMILES
– CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1
Target
– Others
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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