GNE-0439
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GNE-0439

SKU T11437-25 mg Category Brand:

Price range: 2,432 CAD through 4,000 CAD

Products Details

Product Description

– GNE-0439 is a novel Nav1.7-selective inhibitor (IC50: 0.34 uM) and inhibits Nav1.5 (IC50: 38.3 μM). GNE-0439 inhibits mutant N1742K channels (IC50: 0.37 uM) in membrane potential assays.

Web ID

– T11437

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H31NO3

References

– Chernov-Rogan T, et al. Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E792-E801.

CAS Number

– 1241902-40-8

Molecular Weight

– C21H31NO3

SMILES

– CCCC1CCC(CC1)c1ccc(cc1)C(=O)N[C@@H](C(C)C)C(O)=O

Target

– Proton pump

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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