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GLPG2451
Price range: 475 CAD through 2,976 CAD
Products Details
Product Description
– GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator that effectively enhances the function of low-temperature-rescued F508del CFTR with an EC50 of 11.1 nM.
Web ID
– T13705
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C16H16F3N3O5S
References
– Gees M, et al. Identification and Characterization of Novel CFTR Potentiators. Front Pharmacol. 2018 Oct 26;9:1221.
CAS Number
– 2055015-61-5
Molecular Weight
– C16H16F3N3O5S
SMILES
– C[C@H](O)CNC(=O)c1ncc(cc1N)S(=O)(=O)c1ccc(OC(F)(F)F)cc1
Target
– Others
Pathway
– Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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