Download Files:
GLPG0634 analog
$100 – $600
Products Details
Product Description
– GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3[1].
Web ID
– HY-13961
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H18N6O2
References
– [1]Christel Jeanne Marie Menet, et al. Novel compounds useful for the treatment of degenerative and inflammatory diseases. WO2010010190A1.
CAS Number
– 1206101-20-3
Molecular Weight
– 410.43
Compound Purity
– 98.58
SMILES
– O=C(C1CC1)NC2=NN3C(C4=CC=C(OCC5=CC=C(C#N)N=C5)C=C4)=CC=CC3=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 53 mg/mL
Target
– JAK
Isoform
– JAK1;JAK2;JAK3;Tyk2
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
