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Glipizide
SKU
HY-B0254-100 mg
Category Reference compound
Tags Membrane Transporter/Ion Channel, Metabolic Disease, Potassium Channel
$66 – $92
Products Details
Product Description
– Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].
Web ID
– HY-B0254
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C21H27N5O4S
References
– [1]B J Zünkler, et al. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells. Naunyn Schmiedebergs Arch Pharmacol. 1988 Feb;337(2):225-30.|[2]Glipizide. From Wikipedia
CAS Number
– 29094-61-9
Molecular Weight
– 445.54
Compound Purity
– 99.57
SMILES
– O=C(C1=NC=C(C)N=C1)NCCC2=CC=C(S(=O)(NC(NC3CCCCC3)=O)=O)C=C2
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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