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(+)-Glaucarubinone
Products Details
Product Description
– (+)-Glaucarubinone is a potent AP-1 (activator protein-1) inhibitor with an EC50 value of 0.13 µM. (+)-Glaucarubinone shows noncytotoxic[1].
Web ID
– HY-N10926
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H34O10
References
– [1]Diyabalanage T, et al. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4397-9.
CAS Number
– 1259-86-5
Molecular Weight
– 494.53
SMILES
– C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=CC([C@H]2O)=O)=O)OC([C@@](C)(O)CC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– AP-1
Pathway
– Immunology/Inflammation
Product type
– Natural Products
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