(+)-Glaucarubinone

SKU HY-N10926-Get quote Category Tags , ,

Products Details

Product Description

– (+)-Glaucarubinone is a potent AP-1 (activator protein-1) inhibitor with an EC50 value of 0.13 µM. (+)-Glaucarubinone shows noncytotoxic[1].

Web ID

– HY-N10926

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C25H34O10

References

– [1]Diyabalanage T, et al. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4397-9.

CAS Number

– 1259-86-5

Molecular Weight

– 494.53

SMILES

– C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=CC([C@H]2O)=O)=O)OC([C@@](C)(O)CC)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– AP-1

Pathway

– Immunology/Inflammation

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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