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Ginkgetin
Price range: 85 CAD through 1,427 CAD
Products Details
Product Description
– 1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 inhibitor and may be a useful lead molecule for development of a therapeutic STAT3 inhibitor. 4. Ginkgetin induces apoptosis in PC-3 cells via activation of caspase 3 and inhibition of survival genes as a potent chemotherapeutic agent for prostate cancer treatment. 5. Ginkgetin has neuroprotective activity against neurological injury induced by MPTP occurs via regulating iron homeostasis, it may provide neuroprotective therapy for Parkinson’s disease and iron metabolism disorder related diseases.
Web ID
– T4S2126
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H22O10
Citations
– 1. Tang T, Wang X, Qi E, et al. Ginkgetin Promotes M2 Polarization of Microglia and Exert Neuroprotection in Ischemic Stroke via Modulation of PPARγ Pathway. Neurochemical Research. 2022: 1-12
2. Xiao Y, Cai G P, Feng X, et al.Splicing factor YBX1 regulates bone marrow stromal cell fate during aging.The EMBO Journal.2023: e111762.
3. Liu Y, Ye J, Fan Z, et al.Ginkgetin Alleviates Inflammation and Senescence by Targeting STING.Advanced Science.2024: 2407222.
References
– You O H , Kim S H , Kim B , et al. Ginkgetin induces apoptosis via activation of caspase and inhibition of survival genes in PC-3 prostate cancer cells[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(9):2692-2695.
CAS Number
– 481-46-9
Molecular Weight
– C32H22O10
Compound Purity
– 0.9994
SMILES
– COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(OC)c(c1)-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
Pathway
– Immunology/Inflammation|||JAK/STAT signaling|||Apoptosis|||Autophagy|||Stem Cells|||Neuroscience|||Cytoskeletal Signaling
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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