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Gimatecan
$350 – $2,500
Products Details
Product Description
– Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity[1].
Web ID
– HY-B0063
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H25N3O5
References
– [1]Paola Ulivi, et al. Cellular Basis of Antiproliferative and Antitumor Activity of the Novel Camptothecin Derivative, Gimatecan, in Bladder Carcinoma Models. Neoplasia. 2005 Feb;7(2):152-61.
CAS Number
– 292618-32-7
Molecular Weight
– 447.48
Compound Purity
– 99.20
SMILES
– CC(C)(C)O/N=C/C1=C2C(C(N3C2)=CC([C@@]4(O)CC)=C(COC4=O)C3=O)=NC5=CC=CC=C15
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 33.33 mg/mL (ultrasonic;warming;adjust pH to 10 with NaOH;heat to 60°C)
Target
– Topoisomerase
Isoform
– Topo I
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
