GDC-0834
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GDC-0834

SKU T11379-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 317 CAD through 874 CAD

Products Details

Product Description

– GDC-0834 is a potent and selective BTK inhibit that inhibits BTK with an in vitro IC50 of 5.9 nM (biochemical assays) and 6.4 nM (cellular assays), and with an in vivo IC50 of 1.1 μM (mouse) and 5.6 μM (rat).

Web ID

– T11379

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H36N6O3S

References

– Liu L, et al. Antiarthritis effect of a novel Bruton’s tyrosine kinase (BTK) inhibitor in rat collagen-induced arthritis and mechanism-based pharmacokinetic/pharmacodynamic modeling: relationships between inhibition of BTK phosphorylation and efficacy. J

CAS Number

– 1133432-49-1

Molecular Weight

– C33H36N6O3S

SMILES

– CN1CCN(C)C(=O)[C@H]1c1ccc(Nc2nc(cn(C)c2=O)-c2cccc(NC(=O)c3cc4CCCCc4s3)c2C)cc1

Target

– Histone Methyltransferase|||Histone Demethylase

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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