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Products Details
Product Description
– GBD-9, a dual-mechanism degrader, effectively promotes the degradation of BTK and GSPT1 through recruitment of E3 ligase cereblon (CRBN). As a PROTAC molecule, GBD-9 induces BTK degradation, while also acting as a molecular glue for GSPT1 degradation, demonstrating potent inhibition of cancer cell growth [1].
Web ID
– T79139
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C44H47N9O6
CAS Number
– 2864408-92-2
Molecular Weight
– C44H47N9O6
SMILES
– NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(CCCCCCCCNC=6C=C7C(=CC6)C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=O)CCC5)=NC=N1
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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