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Products Details
Product Description
– GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due to its tumor selectivity and specific accumulation. Overexpression of GRPR in pancreatic cancer enables GB-6, when labeled with near-infrared (NIR) fluorescent dyes or the radionuclide technetium-99m (99mTc), to serve as an effective agent for tumor visualization. Demonstrating excellent in vivo stability, GB-6 yields tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW1990 subcutaneous xenograft models. Its rapid tumor targeting capability and precise tumor boundary delineation signify GB-6’s extensive potential for clinical applications [1].
Web ID
– T80266
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H45N11O8
CAS Number
– 2413262-74-3
Molecular Weight
– C32H45N11O8
SMILES
– C([C@H](NC([C@H](CCC(N)=O)N)=O)C(NCCC(N[C@H](C(NCC(N[C@@H](CC1=CN=CN1)C(N)=O)=O)=O)CCC)=O)=O)C=2C=3C(NC2)=CC=C(O)C3
Pathway
– GPCR/G Protein
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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