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Ganoderic acid A
Price range: 62 CAD through 922 CAD
Products Details
Product Description
– 1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation.
Web ID
– T6S1141
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H44O7
Citations
– 1. HAN T, LI Z, ZHANG L, et al.Ganoderic acid A ameliorates renal fibrosis by suppressing the expression of NPC1L1.Biocell.2024
References
– Shao J , Li Z , Jiao G , et al. [Ganoderic acid A suppresses proliferation and invasion and induces apoptosis in human osteosarcoma cells].[J]. Journal of Southern Medical University, 2015, 35(5):619.
CAS Number
– 81907-62-2
Molecular Weight
– C30H44O7
Compound Purity
– 0.9979
SMILES
– C[C@H](CC(=O)C[C@@H](C)C(O)=O)[C@H]1C[C@H](O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)C1C[C@@H]3O
Pathway
– Autophagy|||Apoptosis|||Metabolism|||NF-κB
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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