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G-744
Price range: 5,072 CAD through 9,280 CAD
Products Details
Product Description
– G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM). G-744 is well-tolerated, metabolically stable. It also has an efficacious to treat arthritis.
Web ID
– T15365
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H29N5O3S
References
– Wang X, et al. Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties. ACS Med Chem Lett. 2017 May 3;8(6):608-613.
CAS Number
– 1346669-54-2
Molecular Weight
– C29H29N5O3S
SMILES
– O=C1C2=C(C3=C(S2)CC(C)(C)C3)CCN1C4=C(CO)C(=CC=C4)C=5C=C(NC=6C=CN=CN6)C(=O)N(C)C5
Target
– Others
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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