Fumaric acid

SKU T3763-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 58 CAD

Products Details

Product Description

– Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears due to its ability to inhibit prolyl hydroxylase-containing enzymes.

Web ID

– T3763

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C4H4O4

References

– Chen X, et al. Fumaric acid production by Torulopsis glabrata: engineering the urea cycle and the purine nucleotide cycle. Biotechnol Bioeng. 2015 Jan;112(1):156-67.

CAS Number

– 110-17-8

Molecular Weight

– C4H4O4

Compound Purity

– 0.9928

SMILES

– C(=C/C(O)=O)C(O)=O

Pathway

– Metabolism

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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