FTI-2153
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FTI-2153

SKU T15353-5 mg Category Brand:

Price range: 714 CAD through 4,512 CAD

Products Details

Product Description

– FTI-2153 is a potent and highly selective farnesyltransferase (FTase) inhibitor (IC50: 1.4 nM) that is over 3000-fold more effective at blocking H-Ras (IC50: 10 nM) than Rap1A processing.

Web ID

– T15353

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H30N4O3S

References

– Sun J, et al. Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine. Cancer Res. 1999 Oct 1;59(19):4919-26.

CAS Number

– 344900-92-1

Molecular Weight

– C25H30N4O3S

SMILES

– COC(=O)[C@H](CCSC)NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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