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Products Details
Product Description
– FTase-IN-1 (compound 17a) is a potent and specific inhibitor of fanesyl transferase (FTase) with an IC50 of 0.35 μM. FTase-IN-1 displays cytotoxicity potential and antitumor activity[1].
Web ID
– HY-149015
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H16N2O2S
References
– [1]Iuliana-Monica Moise, et al. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity. Bioorg Chem. 2020 Oct; 103: 104184.
CAS Number
– 2490538-41-3
Molecular Weight
– 384.45
SMILES
– CC(C1=CC(C(C2=CC=C3NC4=C(C=CC=C4)SC3=C2)=O)=C5C=CC=CN15)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Farnesyl Transferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
