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FT671
Price range: 3,392 CAD through 5,920 CAD
Products Details
Product Description
– FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).
Web ID
– T12621L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H23F4N7O3
Citations
– 1. Xu X, Zhang S, Wang Y, et al. Virtual Screening Inhibitors of Ubiquitin-specific Protease 7 combining Pharmacophore Modeling and Molecular Docking. Molecular Informatics. 2022
2. Li H, Sun Y, Yin H, et al.Virtual screening of natural products targeting ubiquitin-specific protease 7.Journal of Biomolecular Structure and Dynamics.2024: 1-8.
References
– Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486.
CAS Number
– 1959551-26-8
Molecular Weight
– C24H23F4N7O3
SMILES
– OC1(Cn2cnc3n(ncc3c2=O)-c2ccc(F)cc2)CCN(CC1)C(=O)C[C@@H](C(F)F)n1ccc(F)n1
Target
– Others
Pathway
– Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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