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Products Details
Product Description
– FPDT is an anti-glioblastoma agent. FPDT displays the IC50 value of 45–68 μM for GBM cells and >100 μM for astrocytes. Anti-glioblastoma activity of FPDT is linked to downregulation of the AKT pathway[1].
Web ID
– HY-147789
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H12FNO2S
References
– [1]Szeliga M, et al. Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway. Bioorg Chem. 2020;105:104362.
Molecular Weight
– 301.34
SMILES
– OC1=CC=C(C(O)=C1)C2=CC=C(S2)NC3=CC=C(C=C3)F
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Akt
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
