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FP-Biotin
$1,500
Only 1000 item(s) left in stock.
Products Details
Product Description
– FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads[1][2][3].
Web ID
– HY-136924
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Molecular Formula
– C27H50FN4O5PS
References
– [1]Baggelaar MP, et al. Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases. ACS Chem Biol. 2017;12(3):852-861.|[2]Grigoryan H, et al. Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine. Chem Biol Interact. 2009;180(3):492-498.|[3]Schopfer LM, et al. Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase. Chem Res Toxicol. 2005;18(4):747-754.
CAS Number
– 259270-28-5
Molecular Weight
– 592.75
Compound Purity
– 99.84
SMILES
– O=P(F)(CCCCCCCCCC(NCCCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)=O)OCC
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– FAAH
Pathway
– Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
