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FOY 251

SKU HY-19727A-10 mg Category Reference compound Tags Anti-infection;Metabolic Enzyme/Protease, Metabolic Disease, SARS-CoV;Ser/Thr Protease

$250 – $2,000

Size

5 mg 10mM/1mL 10 mg 25 mg 50 mg 100 mg

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Products Details

Product Description

– FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor[1][2]. FOY 251 inhibits SARS-CoV-2 infection in cells assay[1][3].

Web ID

– HY-19727A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C17H19N3O7S

References

– [1]K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6.|[2]Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27(1):181-9.|[3]Markus Hoffmann, et al. Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. bioRxiv. 2020 Aug 5;2020.08.05.237651.

CAS Number

– 71079-09-9

Molecular Weight

– 409.41

Compound Purity

– 98.86

SMILES

– O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 20 mg/mL (ultrasonic;adjust pH to 5 with HCl)

Target

– SARS-CoV;Ser/Thr Protease

Pathway

– Anti-infection;Metabolic Enzyme/Protease

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.