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Fosphenytoin (disodium)
SKU
HY-B1657A-10 mg
Category Reference compound
Tags Membrane Transporter/Ion Channel, Neurological Disease, Sodium Channel
$50 – $190
Products Details
Product Description
– Fosphenytoin sodium is a phenytoin proagent with similar anticonvulsant properties. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials.
Web ID
– HY-B1657A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H13N2Na2O6P
References
– [1]Chan SA, et al. Fosphenytoin reduces hippocampal neuronal damage in rat following transient global ischemia. Acta Neurochir (Wien). 1998;140(2):175-80.|[2]Loscher W, et al. Anticonvulsant effect of fosphenytoin in amygdala-kindled rats: comparison with phenytoin. Epilepsy Res. 1998 Mar;30(1):69-76.
CAS Number
– 92134-98-0
Molecular Weight
– 406.24
Compound Purity
– 99.81
SMILES
– O=C1N(COP(O[Na])(O[Na])=O)C(C(C2=CC=CC=C2)(C3=CC=CC=C3)N1)=O
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– H2O : ≥ 100 mg/mL
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.