Fosaprepitant dimeglumine
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Fosaprepitant dimeglumine

SKU T1790-5 mg Category Brand:

Price range: 72 CAD through 590 CAD

Products Details

Product Description

– Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, a water-soluble, N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent selectively binds to human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS), inhibiting receptor binding of endogenous substance P and preventing substance P-induced emesis.

Web ID

– T1790

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C37H56F7N6O16P

References

– Navari RM. Expert Opin Investig Drugs, 2007, 16(12), 1977-1985.

CAS Number

– 265121-04-8

Molecular Weight

– C37H56F7N6O16P

Compound Purity

– 0.9739

SMILES

– CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.C[C@@H](O[C@H]1OCCN(Cc2nn(c(=O)[nH]2)P(O)(O)=O)[C@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

Target

– Others

Pathway

– Neuroscience|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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