Flubendazole

$72$108

Products Details

Product Description

– Flubendazole is a safe and efficacious anthelmintic agent, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle[1][2].

Web ID

– HY-B0294

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C16H12FN3O3

References

– [1]Michaelis M, et al. Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen. Sci Rep. 2015 Feb 3;5:8202.|[2]Zhou X, et al. Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis. Cell Death Discov. 2018 Feb 14;4:18.

CAS Number

– 31430-15-6

Molecular Weight

– 313.28

Compound Purity

– 99.01

SMILES

– O=C(OC)NC1=NC2=CC=C(C(C3=CC=C(F)C=C3)=O)C=C2N1

Clinical Information

– Launched

Research Area

– Cancer; Infection

Solubility

– DMSO : 4.17 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL

Target

– Apoptosis;Microtubule/Tubulin;Parasite

Pathway

– Anti-infection;Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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