Flindokalner
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Flindokalner

SKU T15286-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 811 CAD

Products Details

Product Description

– Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. It is also a positive modulator of large conductance calcium-activated K channels (BKca) and displays negative modulatory activity at Kv7.1 channels (Ki = 3.7 μM). Additionally, Flindokalner acts as a negative modulator of GABAA receptors and demonstrates anxiolytic efficacy in vivo.

Web ID

– T15286

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H10ClF4NO2

References

– Korsgaard MP, et al. Anxiolytic effects of Maxipost (BMS-204352) and retigabine via activation of neuronal Kv7channels. J Pharmacol Exp Ther. 2005 Jul;314(1):282-92.

CAS Number

– 187523-35-9

Molecular Weight

– C16H10ClF4NO2

Compound Purity

– 0.9996

SMILES

– COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F

Target

– Others

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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