Flavokawain 1i
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Flavokawain 1i

SKU T83890-1 mg Category Brand:

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Products Details

Product Description

– Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties. At a concentration of 30 µM, it suppresses the growth of gefitinib-resistant H1975 non-small cell lung cancer (NSCLC) cells by 36% and modulates the protein expression by reducing the levels of heat shock protein 90 (Hsp90) client proteins, including EGFR, c-Met, HER2, Akt, and cyclin-dependent kinase 4 (Cdk4), while increasing the levels of Hsp70, indicative of Hsp90 inhibition. Additionally, intramuscular injection of flavokawain 1i lowers viral loads in pigs afflicted with porcine reproductive and respiratory syndrome virus (PRRSV).

Web ID

– T83890

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H18O4

CAS Number

– 1098176-51-2

Molecular Weight

– C21H18O4

SMILES

– COC1=C(C(O)=CC(OC)=C1)C(/C=C/C2=C3C(C=CC=C3)=CC=C2)=O

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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