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FITC-Dextran (MW 10000)
$50 – $400
Products Details
Product Description
– FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3].
Web ID
– HY-128868
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– N/A
Citations
– Adv Sci (Weinh). 2021 Aug 16;e2101912.|Cell Tissue Res. 2022 Jul 4.|Exp Brain Res. 2021 Jan;239(1):341-350.|Heliyon. 2023 Jul 13.|Immun Inflamm Dis. 07 September 2022.|Immunobiology. 2022: 152315.|J Steroid Biochem Mol Biol. 2023 Apr 21;106314.|Nat Metab. 2022 Sep;4(9):1138-1149.|Research Square Print. 2023 Feb 23.|SSRN. 2023 Jun 12.|Theranostics. 2023; 13(6):2040-2056.|Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282.|Bioengineered. 2022 Feb;13(2):3680-3693.|Bioengineered. 2022 Mar;13(3):7209-7220.|Biomaterials. 1 June 2022, 121608.|Brain Behav Immun. 2023 Feb 27;S0889-1591(23)00050-8.|Cell Rep. 2023 Apr 4;42(4):112346.|Cell Rep. 2023 Jun 20;42(7):112660.|Curr Issues Mol Biol. 2022 Nov 29;44(12):5995-6005.|EBioMedicine. 2022 Jul 28;82:104181.|Exp Brain Res. 2021 Jan;239(1):341-350.|Food Funct. 23rd October 2021.|Front Pharmacol. 02 November 2021.|J Ethnopharmacol. 2023 Aug 26;117098.|Neurotox Res. 2022 May 7.|Phytomedicine. 2023 Apr 21, 154825.|Research Square Preprint. 2023 Oct 10.|Research Square Preprint. 2023 Oct 23.|Sci Adv. 2023 Oct 20;9(42):eadi0699.
References
– [1]Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1).|[2]Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15.|[3]Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189.|[4]Okabayashi K, et al. Cdc42 activates paracellular transport in polarised submandibular gland cells. Arch Oral Biol. 2021 Dec;132:105276.|[5]Yu W, et al. ACE2 contributes to the maintenance of mouse epithelial barrier function. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282.
CAS Number
– 60842-46-8
Molecular Weight
– 10000.00(Average)
SMILES
– [FITC-Dextran
(MW 10000)]
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– H2O : 50 mg/mL (ultrasonic)
Target
– Fluorescent Dye
Pathway
– Others
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
