Fingolimod
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Fingolimod

SKU T7939-1 g Category Brand:

Price range: 48 CAD through 253 CAD

Products Details

Product Description

– Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).

Web ID

– T7939

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H33NO2

Citations

– 1. Wang X, Li X, Wang J, et al. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. Journal of Cell Biology. 2022, 221(7): e202111125 2. Zhang T, Wang Y, Li Q, et al. Mesenchymal stromal cells equipped by IFNα empower T cells with potent anti-tumor immunity. Oncogene. 2022: 1-16. 3. Zhang J, Wang Z, Wei X, et al.The suppression of the SPHK1/S1P/S1PR3 signaling pathway diminishes EGFR activation and increases the sensitivity of non-small cell lung cancer to gefitinib.Current Research in Pharmacology and Drug Discovery.2025: 100212.

References

– Szepanowski, Fabian, Derksen, Angelika, Steiner, Irina,et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling[J]. Journal of Neuroinflammation, 13(1):143.

CAS Number

– 162359-55-9

Molecular Weight

– C19H33NO2

Compound Purity

– 0.996

SMILES

– CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1

Pathway

– GPCR/G Protein|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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