FIIN-2
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FIIN-2

SKU T6836-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 507 CAD

Products Details

Product Description

– FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.

Web ID

– T6836

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H38N8O4

Citations

– 1. Yang Y L, Cao L B, He W R, et al. Endocytosis triggers V-ATPase-SYK–mediated priming of cGAS activation and innate immune response. Proceedings of the National Academy of Sciences. 2022, 119(43): e2207280119.

References

– Tan L, et al. Proc Natl Acad Sci U S A. 2014, 111(45), E4869-4877.

CAS Number

– 1633044-56-0

Molecular Weight

– C35H38N8O4

Compound Purity

– 0.9934

SMILES

– COc1cc(OC)cc(c1)N1Cc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc2N(Cc2ccc(NC(=O)C=C)cc2)C1=O

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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