FIIN-1
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FIIN-1

SKU T37426-1 mg Category Brand:

Price range: 115 CAD through 3,568 CAD

Products Details

Product Description

– FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2, FGFR3, FGFR4, with IC50 of 9.2, 6.2, 11.9 and 189 nM. FIIN-1 inhibited FGFR1, FGFR2, FGFR3 and FGFR4, with IC50s of 9.2, 6.2, 11.9 and 189 nM, respectively.

Web ID

– T37426

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H39Cl2N7O4

References

– Zhou W, et al. A structure-guided approach to creating covalent FGFR inhibitors. Chem Biol. 2010 Mar 26;17(3):285-95.

CAS Number

– 1256152-35-8

Molecular Weight

– C32H39Cl2N7O4

Compound Purity

– 0.973

SMILES

– C(N1C=2C(CN(C1=O)C3=C(Cl)C(OC)=CC(OC)=C3Cl)=CN=C(NCCCCN(CC)CC)N2)C4=CC(NC(C=C)=O)=CC=C4

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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