Fiboflapon

SKU T11487-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 82 CAD through 1,032 CAD

Products Details

Product Description

– Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.

Web ID

– T11487

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C38H43N3O4S

References

– Lorrain DS, et al. Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. Eur J Pharmacol. 2010 Aug 25;640(1-3):211-8.

CAS Number

– 936350-00-4

Molecular Weight

– C38H43N3O4S

Compound Purity

– 0.9701

SMILES

– CCOc1ccc(cn1)-c1ccc(Cn2c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c3cc(OCc4ccc(C)cn4)ccc23)cc1

Target

– JNK

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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