FGTI-2734 mesylate (1247018-19-4 free base)
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FGTI-2734 mesylate (1247018-19-4 free base)

SKU T11282L-25 mg Category Brand:

Price range: 3,408 CAD through 5,968 CAD

Products Details

Product Description

– FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.

Web ID

– T11282L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H35FN6O5S2

References

– Kazi A, et al. Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors. Clin Cancer Res. 2019 Jun 21.

CAS Number

– 2702297-24-1

Molecular Weight

– C27H35FN6O5S2

SMILES

– OS(=O)(C)=O.O=S(C1=NC=CC=C1)(N(CCN(C2=CC=C(C#N)C=C2F)CC3=CN=CN3C)CC4CCCCC4)=O

Target

– ADC Linker

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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