FGTI-2734
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FGTI-2734

SKU T11282-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 75 CAD through 1,406 CAD

Products Details

Product Description

– FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localization of KRAS, addressing the issue of KRAS resistance and inhibiting the growth of mutant KRAS patient-derived pancreatic tumors.

Web ID

– T11282

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H31FN6O2S

References

– Kazi A, et al. Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors. Clin Cancer Res. 2019 Jun 21.

CAS Number

– 1247018-19-4

Molecular Weight

– C26H31FN6O2S

Compound Purity

– 0.9936

SMILES

– Cn1cncc1CN(CCN(CC1CCCCC1)S(=O)(=O)c1ccccn1)c1ccc(cc1F)C#N

Target

– Others

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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