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Ferroptosis-IN-3

SKU HY-149670-Get quote Category Tags , ,

Products Details

Product Description

– Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation[1].

Web ID

– HY-149670

Shipping

– Room temperature

Molecular Formula

– C15H11ClN2O2

References

– [1]Ying Danzhi, et al. Discovery of 4-hydroxyl pyrazole derivatives as potent ferroptosis inhibitors. European Journal of Medicinal Chemistry Available online 4 November 2023, 115913.

Molecular Weight

– 286.71

SMILES

– OC1=C(C2=CC=C(O)C=C2)NN=C1C3=CC=C(Cl)C=C3

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Ferroptosis

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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