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Fenclonine
SKU
HY-B1368-1 g
Category Reference compound
Tags Cancer; Neurological Disease, Metabolic Enzyme/Protease, Tryptophan Hydroxylase
$55 – $66
Products Details
Product Description
– Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research[1][2][3].
Web ID
– HY-B1368
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C9H10ClNO2
References
– [1]M Jouvet. Sleep and serotonin: an unfinished story. Neuropsychopharmacology. 1999 Aug;21(2 Suppl):24S-27S.|[2]A K Sanyal, et al. Prostaglandins: antinociceptive effect of prostaglandin E1 in the rat. Clin Exp Pharmacol Physiol. 1977 May-Jun;4(3):247-55.|[3]Shyamshree S S Manna, et al. Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine. Behav Pharmacol. 2015 Apr;26(3):268-81.
CAS Number
– 7424-00-2
Molecular Weight
– 199.63
Compound Purity
– 99.92
SMILES
– NC(CC1=CC=C(Cl)C=C1)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic;adjust pH to 2 with HCl)|H2O : 4.55 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)
Target
– Tryptophan Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.