FASN-IN-4 (tosylate)

$228$2,400

Products Details

Product Description

– FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29)[1]. FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM[2].

Web ID

– HY-12648A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C33H35N3O7S2

Citations

– Sci China Life Sci. 2021 May 27;1-21.|Cell Biosci. 2022 Sep 16;12(1):158.|Nat Metab. 2021 Sep 27;1-10.

References

– [1]Junjun Chu, et al. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021 Nov;3(11):1466-1475.|[2]Nicholas D. Adams, et al. Fatty acid synthase inhibitors. WO2012064642A1.

CAS Number

– 2095432-57-6

Molecular Weight

– 649.78

Compound Purity

– 99.84

SMILES

– OS(C1=CC=C(C)C=C1)(=O)=O.O=C2COC3(CCN(S(=O)(C4=CC=C(C5=CC=C6C=CC=NC6=C5)C=C4)=O)CC3)CN2C7CC7

Clinical Information

– No Development Reported

Research Area

– Infection; Metabolic Disease

Solubility

– DMSO : 12.5 mg/mL (ultrasonic)

Target

– Fatty Acid Synthase (FASN);SARS-CoV

Pathway

– Anti-infection;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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