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Products Details
Product Description
– FAK-IN-24 (Compound 9f) is a potent FAK inhibitor with an IC50 of 0.815 nM. It induces DNA damage and apoptosis, and exhibits activity against glioblastoma. FAK-IN-24 effectively inhibits proliferation of glioblastoma cell lines U87-MG (IC50= 15 nM) and U251 (IC50= 20 nM), and suppresses tumor growth in U87-MG xenograft models.
Web ID
– T205467
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H45Cl2F3N8O3
CAS Number
– 3062175-62-3
Molecular Weight
– C39H45Cl2F3N8O3
SMILES
– O=C(OCCN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC=4C=CC=CC4C(=O)NC)C(F)(F)F)CC1)CCCC5=CC=C(C=C5)N(CCCl)CCCl
Pathway
– Cytoskeletal Signaling|||Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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