Products Details

Product Description

– FAK-IN-15 (Compound 9b) is a focal adhesion kinase (FAK) inhibitor with an IC50 value of 0.2691 nM. FAK-IN-15 has anti-tumor activity with an IC50 value of 1.033 μM against U87-MG cells[1].

Web ID

– HY-155440

Shipping

– Room temperature

Molecular Formula

– C21H24ClN7OS

References

– [1]Long Z, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023 Nov;140:106792.

Molecular Weight

– 457.98

SMILES

– O=C(C1=C(NC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)C=CS1)NC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– FAK

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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