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Products Details
Product Description
– FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase[1].
Web ID
– HY-155439
Shipping
– Room temperature
Molecular Formula
– C21H24BrN7OS
References
– [1]Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.
CAS Number
– 2766666-22-0
Molecular Weight
– 502.43
SMILES
– CN(CC1)CCN1C(C=C2)=CC=C2NC3=NC=C(Br)C(NC4=C(C(NC)=O)SC=C4)=N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FAK
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
