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Products Details
Product Description
– FAK-IN-11 (Compound 4l) is a FAK inhibitor. FAK-IN-11 binds to the ATP binding pocket of FAK, and inhibits phosphorylation of FAK protein. FAK-IN-11 shows cytotoxic activity against the MDA-MB-231 cells with an IC50 of 13.73? μM. FAK-IN-11 induces non-apoptotic cell death in MDA-MB-231 cells[1].
Web ID
– HY-156026
Shipping
– Room temperature
Molecular Formula
– C25H41NO3
References
– [1]Chawengrum P, et al. The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation. Sci Rep. 2023 Aug 18;13(1):13456.
Molecular Weight
– 403.60
SMILES
– O=C(NOC1CCCCO1)/C=C(C)/CC[C@H]2C(CC[C@@]3([H])C(C)(C)CCC[C@]23C)=C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– FAK
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
