FA16
Add to CompareAdded to Compare

Download Files:

FA16

SKU T64357-1 mg Category Brand:

Price range: 312 CAD through 5,888 CAD

Products Details

Product Description

– FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-)-mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.

Web ID

– T64357

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H27F3N4O2S

References

– Fang Y, et al. Discovery and optimization of 2-(trifluoromethyl)benzimidazole derivatives as novel ferroptosis inducers in vitro and in vivo. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114905.

Molecular Weight

– C22H27F3N4O2S

Compound Purity

– 0.9981

SMILES

– FC(F)(F)C(N=C1C2C=CC=C1)N2CC(CC3)CCN3C4=CC=C(S(N(C)C)(=O)=O)C=C4

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Mephenesin
Mephenesin Price range: 53 CAD through 173 CAD
1 g10 g5 g

1000 in stock

Select options
6-Mercaptopurine
6-Mercaptopurine Price range: 50 CAD through 190 CAD
1 g1 mL * 10 mM (in DMSO)25 mg

1000 in stock

Select options
Mexenone
Mexenone Price range: 48 CAD through 157 CAD
1 mL * 10 mM (in DMSO)100 mg200 mg

1000 in stock

Add to cart
4-(Imidazol-1-yl)phenol
4-(Imidazol-1-yl)phenol 46 CAD

1000 in stock

Select options
7-Chloro-4-(piperazin-1-yl)quinoline
7-Chloro-4-(piperazin-1-yl)quinoline Price range: 56 CAD through 77 CAD
100 mg200 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });